Easton, Ohio — Once again, Leslie H. Wexner has seized upon a small brand and is preparing to blow it out.

He did it with Victoria’s Secret and Abercrombie & Fitch. Now his vision is to modernize the mom-and-pop apothecary by reinventing C.O. Bigelow, the 166-year-old Greenwich Village institution filled with everything from homeopathic remedies to niche beauty products, and a lot of lore.

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