WASHINGTON — The U.S. Environmental Protection Agency and L’Oréal said Monday they will collaborate on a $1.2 million research project funded by the cosmetic giant that is aimed at testing 20 chemicals critical in manufacturing cosmetic products in order to create alternatives to traditional animal-based toxicity tests.
The new research project, unveiled at a news conference at the annual Society of Toxicology meeting in San Francisco, follows an initial smaller collaboration the EPA did with L’Oréal in 2007 and is directed at the potential impact chemicals have on processes in the human body that lead to adverse health effects, said Jared Blumenfeld, EPA administrator for the Pacific Southwest.
Blumenfeld said the EPA has to date tested 1,000 of the 80,0000 chemicals produced worldwide.
“It is amazing that there are about 80,000 chemicals in production worldwide,” said Blumenfeld. “We have very little information on them, so in an effort to move away from animal testing as the main way of determining the response of chemicals and what they will likely be on humans, we created a computer prediction model called ToxCast.”
The EPA launched the computer model and chemical toxicity forecaster in 2007 to test the impact of chemicals on the human body, Blumenfeld said in a phone interview.
So far, the federal government has spent more than $30 million to develop the computer model and test the safety of chemicals, he said.
One of the objectives in partnering with L’Oréal is to determine whether the ToxCast can be used in systemic toxicity tests. L’Oréal is also providing “robust safety data” from a set of chemicals in the cosmetics sector that will expand the types of chemicals assessed by the system.
Laurent Attal, executive vice president at L’Oréal research and innovation, said the company has invested in animal-free toxicology research for more than 30 years.
“Our new L’Oréal Predictive Evaluation Center’s activity is based on new-generation tests, using reconstructed human tissues and automated platforms and will help us to predict earlier the safety of substances for our products,” Attal said.
Patricia Pineau, scientific communications director at L’Oréal, said at the news conference that L’Oréal has invested roughly $800 million in finding new science and technology to replace animal testing over the decades.
“The ToxCast program is really something powerful for what we are requiring” to fully replace animal testing, Pineau said. “The factual data [it provides] we hope will validate the fact that ToxCast will be really one of the tools we need to have in order to end animal testing for chemical toxicology in particular for the cosmetics industry.”
The European Union instituted an animal-testing ban on finished cosmetics products in 2004, followed by a ban on animal testing on ingredients in 2009 and a final ban on marketing animal-tested cosmetics and ingredients in those cosmetics by March 2013. Pineau stressed that L’Oréal committed to moving away from animal testing on finished cosmetics in 1989. “There is a reason large companies still do animal testing, because up until this point, computer models haven’t been sophisticated enough to replace it,” Blumenfeld said. “We hope that ToxCast can finally be that model.”
Blumenfeld said once the testing is done on the computer model, the findings will be made public and will not have to be analyzed again by other companies.
“My personal philosophy to beauty is paying attention to oneself. I love to be outdoors, lots of fresh air, trying to take care of yourself as best you can. I always notice that comes through,” says Felicity Jones, the global face of @shiseido-owned @cledepeaubeauteus, which launches today. Head to WWD.com to read more about the actress’ love for beauty and how she prepared for her new role in “The Basis of Sex,” playing the young Ruth Bader Ginsburg. #wwdbeauty (📷: @dandoperalski)
For men’s fall 2018, @giuseppezanotti drew on elements from streetwear, sport, biker, combat and rock ‘n’ roll. Pictured here are a pair of shoes from the collection, featuring zippers, rhinestones, and silver hardware. Head to WWD.com to see a roundup of the accessories from Milan’s men’s fall 2018 shows. #wwdfashion (📷: Andrea Delb)
To celebrate the 25th anniversary of @ralphlauren’s snowboarding collection, the brand is mining its archives. The iconic brand is reintroducing vintage styles and dropping new designs for a color capsule that will be available in Ralph Lauren stores and @openingceremony on January 25. The capsule will consist of 10 pieces, including the Snow Beach Pullover, pictured here, which is a collector’s item that rapper Raekwon wore in Wu-Tang Clan’s “Can It Be All So Simple” video. #wwdfashion (📷: Tom Gould)
For @rochasofficial’s pre-fall 2018 collection, creative director Alessandro Dell’Acqua channeled the sophisticated and intriguing Catherine Denevue in the film “Belle de Jour.” Polished collarless coats, midi skirts, suits and ’60s graphic motifs were all featured in the collection, adding a sense of discreet luxury. See the rest of the photos on WWD.com #wwdfashion
“We tried to produce clothing of that couture quality, but the most daunting part was that we only had a matter of days [to do it],” said costume designer Lou Eyrich, who recreated Gianni Versace’s iconic looks for @americancrimestoryfx. Eyrich searched online retailers and vintage shops for original pieces from the design house and for @penelopecruzoficial, who plays Donatella Versace. Head to WWD.com to read how she created the Versace world. #wwdfashion
Only three months after her stellar debut catwalk season, @kaiagerber has inked her first big design collaboration –– with @karllagerfeld. The collection blends Lagerfeld’s Parisian chic aesthetic and the model’s signature West Coast casual style via RTW, accessories, footwear and more. The #KarlLagerfeldxKaia collection will launch in September with a series of events. Get all the details on WWD.com. #wwdnews #wwdfashion
Harrods plans to remove the famous statue of Princess Diana and Dodi Al Fayed from the bottom of the Egyptian escalators and hand it back to Mohamed Al-Fayed. “We are very proud to have played our role in celebrating the lives of Diana, Princess of Wales and Dodi Al Fayed at Harrods and to have welcomed people from around the world to visit the memorial for the past 20 years,” said Michael Ward, Harrods managing director. “With the announcement of the new official memorial statue to Diana, Princess of Wales at Kensington Palace, we feel that the time is right to return this memorial to Mr. Al Fayed and for the public to be invited to pay their respects at the palace.” More on the news, with reporting by @loreleimarfil, at WWD.com. #wwdnews