Cuthbertson, whose focus will be on product, will start his new job on Jan. 2, succeeding Jacqui Markham, who had assumed a consultancy role with the brand around six months ago.
Cuthbertson will join creative director David Hägglund, who was appointed last year. Hägglund had succeeded Kate Phelan and Gordon Richardson. He will oversee a design department comprised of 72 employees, and report to Paul Price, the new chief executive officer of Topshop and Topman.
Cuthbertson was most recently design director of Just Cavalli and had served as the creative director of the Australian denim and contemporary label Sass & Bide. He also worked as a creative consultant at Victoria Beckham and Mulberry.