NEW YORKSaks Fifth Avenue and the Entertainment Industry Foundation are counting on Julianne Moore and Jason Wu to be a winning combination for this year’s Key to the Cure campaign.

In its 17th year, the 2015 installment will be the first time Saks is teaming up with Stand Up to Cancer, an EIF offshoot created to fuel innovative cancer research through collaboration among leading scientists from different institutions and disciplines.

The limited edition Wu-designed Key to the Cure T-shirt that Moore models in PSAs will go on sale Oct. 1. The Oscar-winning actress said, “Everyone has been affected by cancer in some way, whether you’ve known or cared for a loved one facing a cancer diagnosis, or contended with cancer yourself. So I’m honored to work with the Entertainment Industry Foundation and Saks Fifth Avenue to highlight Stand Up to Cancer’s mission to make everyone diagnosed with cancer a survivor.”

Reached in his New York studio, Wu, whose fondness for midcentury artists is a source of inspiration, said he started the concept with brushstrokes that were re-imagined and scanned. The end result resembled a key within a painting. “There are so many graphic Ts already out there. We felt it was really important to create one that was refined. And it’s very loud and clear that it is for Key to the Cure,” Wu said. “We also really wanted to create something that was elevated, sophisticated and feminine that reflected the essence of the brand.”

All sales of his $35 creation will benefit Stand Up to Cancer. It will be sold this fall in Saks Fifth Avenue stores and online via both the Saks and Saks Off 5th Web sites. Beyond the cancer research component, Wu also has a personal connection to Saks, which was one of the first stores to carry his signature label eight years ago. In addition, he has dressed Moore for numerous red-carpet occasions and she was front row at his Boss runway show in February.

Thus far, Saks has donated more than $36 million to women’s cancer research and treatment organizations in the U.S. including the Breast Cancer Research Foundation; EIF’s Women’s Cancer Research Fund; Cleveland Clinic; Boston’s Dana-Farber Cancer Institute, and Nevada Cancer Institute. Saks president Marc Metrick said, “We look forward to Key to the Cure every October. It’s really great to see our stores, customers and vendors rally together to support such a great cause in raising awareness and funds.”

EIF president and chief executive officer and cofounder of Stand Up to Cancer Lisa Paulsen said, “The Entertainment Industry Foundation is proud to continue to join forces with Saks Fifth Avenue in our shared mission to fund innovative cancer research that is getting new treatments to the patients who need them quickly.”

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