Jennifer Aniston is headlining Saks Fifth Avenue’s 2013 Key to the Cure campaign.

As the Entertainment Industry Foundation ambassador for the initiative, the actress will appear in ads wearing this year’s limited-edition T-shirt designed by Emilio Pucci’s Peter Dundas. As of Oct. 1, shoppers will find the $35 item at Saks and Saks Off 5th stores, as well as All proceeds will be donated to the EIF’s Women’s Cancer Research Fund, which benefits charitable programs seeking new detection methods, better treatments and potential cures for cancers that affect women.

This story first appeared in the June 21, 2013 issue of WWD. Subscribe Today.

Aniston follows in the ranks of former EIF ambassadors such as Penélope Cruz, Jennifer Hudson and Uma Thurman. For the national public service announcement, Aniston paired Dundas’ white shirt with a gray heart-shaped design with slim jeans and an oversize brown leather belt. The image will run in September and October issues of major fashion and lifestyle magazines. While tabloids continue to debate the status of her wedding plans with Justin Theroux, who has just signed up for HBO’s “The Leftovers,” Aniston made her 8-carat engagement ring easy to spot by posing with her left hand on her left shoulder. Next month she starts filming “Squirrel to the Nuts,” directed by Peter Bogdanovich.

She said, “My hope is that everyone will contribute to this worthy cause by purchasing a Key to the Cure T-shirt designed by Emilio Pucci.”

Saks will stage this year’s charity shopping weekend Oct. 17 to 20 at all Saks and Off 5th stores, and via In the 14 years since Saks launched its first charitable shopping weekend, the retailer has raised more than $33 million for cancer research with the help of its vendors and partners. The Breast Cancer Research Foundation, EIF’s Women’s Cancer Research Fund, the Cleveland Clinic, Boston’s Dana-Farber Cancer Institute and the Nevada Cancer Institute are among the organizations that have benefited from KTTC.

Saks chairman and ceo Stephen I. Sadove said, “In our 15th year, the continued support of our charity affiliates and efforts made by our clients, vendors and associates have proven to be a true testament to the Key to the Cure legacy.”

Dundas also weighed in on the cause. “I think every living person has been touched by this disease through the illness or even the loss of a friend or family member. I have. It would seem that in 2013 this would no longer be a worry, but it very much is so. The fight continues.”