The brand is run by Claudio Marenzi, the second generation of the Italian luxury outerwear brand.
A new algorithm employs measurements from thousands of other men to predict a proper fit.
The six styles of shirts retail for $145 and are available on the J. Hilburn web site.
Seven retailers will be hosted on a trip to Biella, Lake Como and Milan.
The initiative launches on April 4 and will require either self-measurements from customers or a live chat with an associate.