Francesco Risso will become creative director of the label.
The designer had most recently been freelancing after running his own label and working at Cerruti and Jack Wills.
The fragrance pioneer has married his twin passions for perfume and architecture with the opening of his West Village boutique.
The series of 11 temporary venues will be set up simultaneously in eight different countries.
The AFA orchestrated an open talk between the designer and Margaret Russell, editor in chief of Architectural Digest.